Above and beyond these main effects, the life events × GABRA2 interaction effects reached statistical significance for the parental antisocial behavior and alcohol problems models (see Model 2 in Tables 3 and 4). The interactions accounted for 0.47% and 0.46% percent of the variance in the respective models. Figure 1 depicts the mean levels of CBCL externalizing as a function of life events and GABRA2 genotype for the model that included parental antisocial behavior. A consistent pattern of effects was found for the model that included parental alcohol problems (available upon request from the first author). Figure 2 illustrates how the association (depicted as standardized betas and their 95% confidence intervals (CI)) between life events and subsequent CBCL externalizing varied as a function of genotype. In the model that included parental antisocial behavior (Panel A, left) life events predicted subsequent CBCL externalizing for those with no copies of the minor allele (β = 0.06, 95% CI [0.001, 0.12]), but not for those with one or two copies of the minor allele (MA) (β1MA = 0.01, 95% CI [−0.05, 0.06]); β2MA
