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Chunk #12 — Methods — Statistical analysis

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A large-scale genome-wide association study meta-analysis of cannabis use disorder.
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In the iPSYCH cohort, logistic regression was done with imputed dosages, covarying for five ancestral principal components, data processing waves, and the presence of another psychiatric disorder (because iPSYCH was established to study major psychiatric disorders, cases of cannabis use disorder and controls include comorbidity).3 Adding sex as a covariate to iPSYCH analyses has been shown not to alter findings.20