for any one gene is not compelling and the specific findings requires confirmation in additional samples. Also, the close proximity of a number of the genes suggests that there are instances where more than one gene derives from the same association signal (note this phenomenon will inflate the estimated numbers of signals in both observed and permuted datasets and therefore does not impact on the main findings). Table S3 shows those genes which in each of schizophrenia and bipolar disorder surpassed thresholds of smallest p<0.01 or where for either truncation threshold, the product of p was ≤0.01 as these thresholds also correspond to a considerable degree of enrichment in the observed compared with the simulated data.
