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Chunk #26 — Discussion — Selective effects of recent life events related to financial difficulties in interaction with the 5-HTTLPR genotype in the development of depressive symptoms

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Financial difficulties but not other types of recent negative life events show strong interactions with 5-HTTLPR genotype in the development of depressive symptoms.
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method, interacted with the 5-HTTLPR genotype on the structural connectivity between the hippocampus and the amygdala as well as the putamen, and also on the functional connectivity of the parahippocampus with the posterior cingulate cortex.50 These studies provide a strong argument that recent life events in interaction with the 5-HTTLPR genotype influence the activation patterns of brain areas implicated in depressive symptomatology, although the differential effects of types of recent life events have not been studied.