Compared to their nondrinking counterparts, but not to each other, early- and late-onset drinkers were also significantly more likely to have ever used marijuana and cigarettes. However, early-onset drinkers were also significantly more likely to report early cigarette smoking, when compared with both nondrinkers and late-onset drinkers, but no differences were observed across drinking groups for early sexual intercourse. We were not able to examine early marijuana use in a multivariable model owing to the sparseness of the data.