It is important to note that these associations were only observed in left VS after accounting for covariates Although, some studies have found decreased VS reactivity in response to positive stimuli in depressed patients solely in the left hemisphere (Pizzagalli et al. 2009), others have found diminished reactivity bilaterally (Epstein et al. 2006). There is limited understanding of VS laterality leaving us unable to speculate about this laterality finding.
