consumption, in population-based data (13) or in a Native-American sample (14). The lack of evidence for familial influences on remission from AUDs contrasts sharply with evidence that the heritability for the development of AUDs is 50–60% (4, 5, 9), and suggests that a phenotype derived from symptoms that characterize the development of an AUD may be insufficient to test familial influences on remission from that disorder.