Severity of MA dependence was defined by the number of DSM-IV criteria met for MA dependence (3-5 = moderate, 6-7 = severe) (Kalayasiri et al., 2006, Kalayasiri et al., 2010). For MA withdrawal, 9 symptoms were ascertained via the SSADDA, including feeling depressed, feeling restless, feeling fatigued, insomnia, hypersomnia, craving for MA, psychomotor retardation, increased appetite, and having nightmares that occurred most nights for two days or longer when MA use was stopped or reduced. Severity of MA withdrawal was classified into 3 levels including mild, moderate, and severe (1-3, 4-6, and 7-9 symptoms, respectively).
