to examine for increased consistent directionality of effect for the most strongly associated SNPs between the case-control and trio samples. Analyses of potential enrichment of SNPs from: a) 22 previously identified candidate genes, b) pre-defined gene pathways, and c) target gene intervals containing micro-RNA (miRNA) binding sites52, among the top hits from the trio, case-control, or trio-case-control GWAS results were performed using INRICH.40
