Assuming an additive genetic model and a Gaussian-distributed phenotype, 2 235 individuals provide 95% power to detect a genotyped SNP with heritability h2 = 0.02 at significance level 5×10−7, and 39% power for h2 = 0.01. Thus we expect to detect almost all SNPs with h2>0.02 and a large proportion of those with h2>0.01.
