paperKB
coga / coga-kb
Help
Sign in

Chunk #8 — Results/Discussion — In Silico and De Novo Follow-Up

Source
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
Embedded
yes

Text

For these 26 SNPs, we obtained in silico follow-up data from another 8 studies with GWAS data (Stage 2a: maximum N = 13,830 individuals, all European-ancestry), and performed de novo genotyping in subjects from 20 additional studies (Stage 2b: maximum N = 56,859, all European-ancestry) (Table S3). Follow-up analyses were restricted to the precise phenotype(s) (WC and/or WHR) for which the SNP had been selected in stage 1 making a total of 30 SNP-phenotype combinations (Tables S2 and S6).