Regulation). Recent work with major cloud vendors on deployment scripts and automated REDCap upgrade methods have created an opportunity for partners to set up REDCap installations in the cloud, thereby eliminating the need for on-site hardware and reducing local systems administrator support. REDCap’s back-end architecture, all of which runs on open source components, is very flexible and does not force strict requirements for general implementation. REDCap can operate “onpremise” (on the local institution’s hardware servers or virtualized servers) or on various cloud-based infrastructures (e.g., AWS, Azure, Google Cloud). For virtualized setups, REDCap may run as a traditional virtualized web server (e.g., VMware, VirtualBox) or as a containerized service (e.g., Docker, Kubernetes). As new server technologies have developed over the past decade, we have observed a gradual increase among REDCap partner institutions adopting virtualized environments running REDCap, and in more recent years, containerized solutions for supporting the software platform. Minor revisions to the REDCap EULA have clarified licensing for non-U.S. partners and cloud-based installations.