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Chunk #3 — RESULTS — Genomic analysis of iPSC derived from patients with idiopathic ASD

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FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders.
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To analyze neurodevelopmental aspects of idiopathic ASD, we generated iPSC lines from members of four families that each included an ASD proband with increased head circumference (HC) and one to three unaffected, first-degree family members (see Figure S1A for family structure and Table S1 for data collection and participants details).