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Chunk #0 — INTRODUCTION

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Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances.
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Primary tooth eruption is a complex and highly regulated process through which primary teeth enter the mouth and become visible. Prior to eruption, mononuclear cells move to the dental follicle and fuse to form osteoclasts. These osteoclasts subsequently resorb alveolar bone and in doing so form an eruption pathway through which the primary dentition can then emerge (1).