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Chunk #25 — 3. Results — 3.2. Effects of ethanol on gene expression in the ACB

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Gene expression changes in the nucleus accumbens of alcohol-preferring rats following chronic ethanol consumption.
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Comparison of the CA versus MSA group revealed 51 significant differences (p < 0.01). However, the FDR-values for these findings were approximately 0.4, suggesting a high number of false positives. Therefore, this analysis indicated there were few genes with significant expression differences between the two alcohol drinking groups, even though there were a significant number of differences between the CA versus W group but not between the MSA versus W group.