In the PTSD sex-stratified analyses (see Table 1 for heritability estimates), the genetic correlation between AD and the female PTSD sample was again moderate and significant (rg = 0.34, SE = .14, p = .01); however, the genetic correlation between AD and the male-only PTSD sample was not significant, and the point estimate was lower (rg = 0.14, SE = .44, p = .75). An additional set of analyses was conducted in the male PTSD sample, as previous work (Nievergelt et al., 2019) identified different estimates of heritability in males based on samples that comprised the PTSD-PGC2 data (heritability estimates for the separate sub-samples are presented in Table 1). Thus, LDSC analyses were conducted separately for these two male sub-samples (PTSD-PGC1.5 and UKB PTSD). While there was no significant correlation between AD and PTSD in the PGC1.5 sample (rg = −0.25, SE = .60, p = .68), there was a significant correlation between AD and PTSD in the UKB sample (rg = 0.51, SE = .24, p = .04).
