The suggestion that striatal FSIs contribute to the generation of local gamma oscillations is compatible with observations from hippocampus and a number of cortical areas, where there is much support for the role of PV+ FSIs in the generation of gamma oscillations (Buzsáki et al., 1983; Freund and Katona, 2007; Klausberger et al., 2003; Tamás et al., 2000). An open question is whether the intensity of subthreshold gamma oscillations in striatum displays an anatomical gradient consistent with that seen in LFP gamma power (Berke et al., 2004; Masimore, 2008) and if these oscillations synchronize across FSIs; if found, such data would provide further evidence supporting the local generation of ventral striatal gamma oscillations.
