subjected to a single dose. Again, this confers an inherent advantage on feeding in producing post-embryonic phenotypes that can be exploited by those studying genes important later in development. It should be noted, however, that there are gene-specific differences between RNAi by feeding and injection. We found that some genes are more sensitive to RNAi by injection and others to RNAi by feeding (Figure 4). In addition, for some genes, RNAi by feeding is more variable than RNAi by injection. Thus feeding is a useful tool to complement, rather than replace, RNAi by injection.
