The behavioral analysis provided evidence for slowed motor performance in the patients, which varied by task and observed parameters (Fig. 2). In the pressing task, patients and controls performed press-release actions at a similar rate (patients, 0.33 ± 0.08/s; controls, 0.31 ± 0.09/s; Fig. 2Ai). The maximum EMG amplitude did not differ between patients and controls (Fig. 2Aii). Likewise, the EMG slopes (see Fig. 1E) regarding either force build-up or release were similar between patients and controls (force build-up in Fig. 2Aiii; releasing, P > 0.99, data not shown).
