For high-dimensional data, the NIA-supported AMP-AD Knowledge Portal on the Synapse platform is the preferred distributor (Data Citation 1), and additional samples as well as phenotypic and other data are available through the RADC Research Resource Sharing Hub (https://www.radc.rush.edu/). Data from each unique participant is assigned the same 6 digit study ID, facilitating the relation of different data types. To download files see the ‘How to Download’ guide on the folder to download all folder content, and the Synapse documentation for more details: http://docs.synapse.org/articles/downloading_data.html. The following are the key files: (1) Study description (Data Citation 2), (2) Clinical data, codebook and assay ID key (Data Citation 3), (3) Genotypes (Data Citation 4), (4) Genotypes imputed (Data Citation 5), (5) Whole genome sequencing: (Data Citation 6), (6) RNA-Seq (Data Citation 7), (7) miRNA profile: (Data Citation 8), (8) H3K9Ac ChIP-Seq (Data Citation 9), (9) DNA methylation profile (Data Citation 10).
