Functional data were reconstructed using iterative image reconstruction (Sutton et al., 2003, Fessler et al., 2005) and motion-corrected using FSL 4.0 (Analysis Group, FMRIB, Oxford, UK). Runs exceeding 2mm translation or 2° rotation were excluded: six subjects had one run; five subjects had two runs removed. Number of subjects with excluded runs did not differ by resiliency or family history (p’s>0.203), but trended by gender (χ2=3.62, p=0.073). Age of onset and substance use did not differ between subjects with/without excluded runs (p’s>0.234). Image processing was completed using statistical parametric mapping SPM2 (Wellcome Institute of Cognitive Neurology, Oxford, UK). Functional images were spatially normalized to standard stereotactic space as defined by the Montreal Neurological Institute. A 6mm full-width-half-maximum Gaussian spatial smoothing kernel was applied.
