Qrr1 does not have a strong trans-effect in the LXS and CXB hippocampus datasets (table 2). This indicates that the sequence variants underlying the trans-QTLs do not segregate to nearly the same extent in the LXS and CXB RI panels as they do in B6×D2 and B6×C3H crosses. This contrast among crosses can be exploited to parse Qrr1 into sub-regions and identify stronger candidate genes.
