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Chunk #19 — EPs and PDs as a bivariate problem

Source
Endophenotype: a conceptual analysis.
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yes

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As rg approaches 1.0, Figure 4a becomes equivalent to Figure 1a (and this becomes equivalent to the paths for EP and PD coming both from step D in Figure 4b). Obviously, the interest and utility of an EP for a given PD would relate to the value of rg. If rg were quite low, measuring EP would tell you relatively little about the genetic risk for PD.