Electrophysiology has been the preferred means of analyzing brain activity due to the ability to capture a wide range of neural phenomena, from the spiking activity of individual neurons to the slower network oscillations of small populations (Llinás, 1988; Contreras, 2004; Assad et al., 2014). The electrical nature of neuronal activity makes it possible to detect signals on electrodes at a distance from the source, but not without caveats. It is necessary to determine the recording capabilities and limits of the device used and to understand how the neuronal signal is transduced into a recorded digital form. Typical electrophysiological methods are shown in Figure 1 and further described below.