Since this 2019 version of g:GOSt we have enabled users to use any other relevant data sources by accepting custom Gene Matrix Transposed file format (GMT files). Custom GMT file support enables users to find enriched terms that might be specific for their scientific topic or not regularly updated and therefore not selected as default data source for g:Profiler. This allows us to focus our resources on providing limited but high quality and up-to-date data while providing the flexibility of analysing other species or data to the users.