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Chunk #39 — Discussion

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Does electroencephalogram phase variability account for reduced P3 brain potential in externalizing disorders?
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yes

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neurobiological similarity that could help explain comorbidity shared across these disorders. Viewing P3 in terms of its time-frequency energy and phase-locking dynamics may prove to be an important tool for future research to compare and contrast pathophysiological factors for a number of psychiatric disorders. By combinative use of multiple P3-related measures ("multivariate endophenotype"; cf. Gilmore et al., 2010b; Iacono et al., 2000), perhaps greater specificity and statistical power in prediction of certain diagnoses can be achieved.