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Chunk #24 — Results — Haplotype Analyses

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The ankyrin-3 gene is associated with posttraumatic stress disorder and externalizing comorbidity.
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We also examined haplotypes consisting of the four externalizing-associated SNPs (Table 1 SNPs 1–4). We found that the haplotype formed by the four SNPs was more significantly associated with externalizing than any individual SNP (β= −0.5063 and p=0.00025 for the GGAA haplotype). This haplotype was not associated with PTSD (p=0.60).