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Chunk #35 — CLINICAL MANAGEMENT OF MBL — Recommendations for Evaluation and Follow-up

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Monoclonal B-cell lymphocytosis (MBL): biology, natural history and clinical management.
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There exists limited data on the clinical management of patients with MBL. The great majority of individuals with MBL (approximately 85%) are currently identified as part of the clinical evaluation of an abnormal blood count, most commonly lymphocytosis. These individuals with clinical MBL should undergo a complete evaluation by a hematologist/oncologist that includes a detailed family history (given the association between CLL and MBL), a review for B type symptoms, and a complete physical examination with comprehensive lymph node examination.