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Chunk #8 — Materials and Methods — Analysis of WTCCC Type 1 and Type 2 Diabetes Data Under Heterogeneity

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The impact of phenotypic and genetic heterogeneity on results of genome wide association studies of complex diseases.
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Since the QC analysis in the original study was performed across ∼14,000 subjects (compared to the ∼7,000 available for the present study), we also applied exclusion lists supplied in the WTCCC data in addition to in-house QC. The scripts used for QC are available online.