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Chunk #9 — Discussion

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Whole-genome linkage analysis in mapping alcoholism genes using single-nucleotide polymorphisms and microsatellites.
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the SNP scan had a peak at the marker tsc0056805 at 243.6 cM with an NPL score of 2.80. The differing results observed in the two scans were likely explained by the difference between the IC in the microsatellites and the SNPs. In fact, the higher IC is one major advantage of the high-density SNPs compared with the conventional microsatellite sets. The IC across the genome for the SNPs was uniformly higher than that for the microsatellites.