paperKB
coga / coga-kb
Help
Sign in

Chunk #14 — Results — eQTL at a common inversion polymorphism on chromosome 17q21 — Identification of gene expression changes in fetal brain associated with neuropsychiatric traits

Source
Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders.
Embedded
yes

Text

3.76 × 10− 5; eTranscripts, P-SMR < 1.54 × 10− 5). In addition, we only report associations that are non-significant (P > 0.05) for the HEIDI (heterogeneity in dependent instruments) test, indicating that they are unlikely to be driven by linkage between the eQTL and independent risk variants [44]. In total, we identified 15 eGenes and 34 eTranscripts where expression in fetal brain was pleiotropically associated with at least one neuropsychiatric trait and conformed to the above criteria (Additional file 1: Table S8 and Table S9, respectively).