Dipole source analysis provides a tool to identify the generation of neuronal structures and to separate overlapping activity existent in scalp-recorded ERPs (Pockett et al. 2007). In addition, test–retest reliability of P300 could be improved with dipole source analysis, which provides higher test–retest reliability than single channel P300 analysis and principal components analysis (PCA) (Frodl et al. 2000). In this context, dipole source analysis might facilitate P300 applications in psychiatric research.