The EU control sample consisted of 4975 European Caucasian controls primarily derived from cohorts of previously genotyped, unselected population controls (Supplementary Methods). Ancestry-matched controls for the FC (N=196) and SA (N=158) samples were collected in parallel with their respective cases (15, 16). Ancestry-matched controls for individuals with AJ ancestry were identified from the EU control sample based on self-reported ancestry and principal component analysis (N=338).
