Some of the challenges that interview participants reported were due to their role as pioneers of the TD team science approach not only at the intersection of obesity research and cancer research, but also in scientific research more broadly. The challenges they identified related to the absence of a clear definition of TD research, lack of guidelines specifying how to engage in TD team science, and few published exemplars of prior TD team science reflect the novelty of the TD team science approach when TREC I was launched in 2005. Since then, a substantial and growing body of literature has been published that is building an evidence base for how to effectively conceptualize, develop, and implement TD team science initiatives [1-3,5-15,20- 23,26,35-46].
