In summary, we show data that we argue convincingly demonstrates QTLs for DNA methylation and expression exist across human tissues. The data presented here provides an initial basis for understanding how genetic variance in humans influences epigenetic marks and expression; we argue that these observations may be useful in the understanding of gene contributions to human phenotypes. As well as providing a more complete model of the complex control of gene expression in the brain, our data may be useful in moving rapidly from locus to mechanism of disease.
