Table 3 summarizes DALYs assigned to each mental, neurological, and substance use disorder in 2010. These disorders as a group ranked as the third leading cause of DALYs after cardiovascular and circulatory diseases (explaining 11.9% of DALYs) and diarrhoea, lower respiratory infections, meningitis, and other common infectious diseases (explaining 11.4% of DALYs). The greatest variation in burden within the disorder groupings was for mental disorders. Major depressive disorder was responsible for the highest proportion of mental, neurological, and substance use disorder DALYs (24.5%); attention-deficit hyperactivity disorder was responsible for the lowest (0.2%).