EMT is a fundamental cellular process that is involved in epithelial tissue morphogenesis during tissue development and cancer progression. In our previous studies, we demonstrated that EMT was critical to HCC progression and regulated by the GLI1/SNAI1 axis [21, 26, 27]. To reveal the mechanism through which GLI1 and SNAI1 mediate EMT in HCC, we investigated the role of CtBP2 in GLI1/SNAI1 axis induced EMT.
