The difference in heritability estimates (Table 3) between males (h2M=0.131, SE = 0.097) and females (h2F=0.296, SE = 0.079), as determined by LDSC regression, was not statistically significant, and the genetic correlation between the sexes was substantial (rg = 1.043, SE = 0.509, p=0.041). The restricted maximum likelihood analysis (REML) estimates of heritability were almost identical between males (h2M=0.232, se=0.072, p=0.001) and females (h2F=0.240, se=0.057, p=1.07e-05), and to the combined estimate (h2=0.238, se=0.033, p=8.621e-14). The REML genetic correlation between males and females was 1.00 (se=0.27). The observed patterns were also robust across population prevalence rates (Supplementary Table 3).
