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Chunk #11 — Method — Participants

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Resting frontal EEG asymmetry as an endophenotype for depression risk: sex-specific patterns of frontal brain asymmetry.
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During the intake interview administered by a graduate-level trained clinical rater on a separate day before any EEG evaluations, participants were again screened for the same exclusionary criteria covered in the phone screen, and then further screened for Axis I psychopathology using the Structured Clinical Interview for DSM-IV (SCID, First, Spitzer, Gibbon & Williams, 1997). Participants were excluded if they met criteria for any current comorbid DSM-IV Axis I disorder other than lifetime MDD or current dysthymia. Inter-rater reliability analyses (performed by clinical interviewers and the first and last authors) for a randomly selected 10% of SCIDs demonstrated high inter-rater agreement for current and past MDD diagnoses (Kappa = .81 and .91, respectively). The final sample consisted of 306 participants (95 male), with an age range of 17 to 34 years (M = 19.1, SE = 0.1). A total of 143 participants met criteria for the lifetime MDD+ group (Table 1 lists DSM-IV diagnoses for this sample), whereas the remaining 163 participants did not meet criteria for any Axis I disorder and were considered the lifetime MDD- group.