Consistent with these clinical observations, meta-analyses have reported consistent impairments in response inhibition performance [121] and neuroimaging studies have reported reduced IFG and/or caudate activity during response inhibition [122–123] in OCD. Still, not all studies report impairments in response inhibition in individuals with OCD [124–126]. A meta-analysis comparing neuropsychological performance between OCD patients with predominant washing versus checking symptoms reported significantly better response inhibition in washers than checkers [127], suggesting that the presence of response inhibition deficits may depend on the dimension of obsessive-compulsive symptoms.
