where direct tests of responses to alcohol drinking may not be feasible due to logistical factors, underage status, or ineligibility due to a diagnosis of alcohol use or other medical disorder. The relationship between the SRE and results from direct alcohol challenge has also been investigated. In that study the average number of drinks endorsed on the SRE correlated significantly with a participants rating of their level of intoxication following drinking and correctly identified 79% of the participants whose level of response to alcohol fell into the lowest third of intensity during the alcohol challenge (Schuckit et al., 1996). The SRE has been utilized to estimate level of response to alcohol in a number of diverse populations including: middle age women (Schuckit et al., 2003), sons of alcoholics and matched controls (Schuckit et al., 1997b), participants in the collaborative study on the genetics of alcoholism (COGA) (Schuckit et al., 1997a), a military population (Schuckit et al., 2001b), and in African (Pedersen and McCarthy, 2009) and Asian Americans (Wall et al., 1999).