another study, muscarinic blockade was shown to reduce the interaction between theta phase and gamma amplitude in the mouse (Hentschke et al., 2007). The results of these studies have been interpreted as indicating that phase synchronization may play a causal role in memory processes (Sauseng and Klimesch, 2008). Acute alcohol ingestion, especially at higher doses, can cause transient but significant decreases in memory function, that could be associated with reductions in phase locking, but it also produces a number of other behavioral effects including the sensation of intoxication which is presumably the reason for its consumption (Fernandez-Serrano et al., 2011).
