contralateral region through more indirect posterior connections (i.e., posterior commissure/thalamic nuclei) after TAI, and the degree of inefficiency (i.e., diffuse connectivity) seen in the pattern of hippocampal connectivity among patients may be evidence of this plasticity. However, while this plasticity eventually results in neuronal signal reaching its contralateral destination and a relative increase in interhemispheric hippocampal connectivity, it occurs at the expense of memory ability.