We meta-analysed PGC MDD and UKB MDD to obtain a single major depressive disorder GWAS (combined MDD). We meta-analysed combined MDD with PGC BD, comparing mood disorder cases to controls (MOOD). Further meta-analyses were performed between PGC MDD and each bipolar disorder subtype and major depressive disorder subtype to assess the relative increase in variant discovery when adding different mood disorder definitions to PGC MDD (Supplementary Results).
