The MCTFR sample will also soon be genotyped on Ilumina’s HumanExome BeadChip, which includes > 240,000 coding sequence variants. These data, when combined with the original GWAS data, will provide extensive coverage of both common and relatively rare genetic variants in key genetic regions. We are also at the initial stages of planning for whole genome sequencing a large number of MCTFR participants as well as obtaining additional relevant phenotype information. In this era of large scale consortia, the extensive phenotypic, genetic and environmental assessments in the MCTFR will provide numerous opportunities for collaboration.
