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Chunk #30 — Discussion

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Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior.
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dependence criteria. These pieces of evidence suggest that ABCB1 may be a gene of interest for further study. We also found enrichment of several immune-related canonical pathways and gene ontologies, which is consistent with previous suggestions that immune and inflammatory pathways are associated with externalizing spectrum behaviors. As a whole, our study goes beyond the candidate gene approach typically taken in studies of AAB, and implicates a gene and gene sets for which there is convergent evidence from other lines of research. These findings, although novel and promising, would benefit from direct replication.