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Chunk #16 — Results — Principal Component Analysis also Shows Other Aspects of Genomic Architecture

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Analysis and application of European genetic substructure using 300 K SNP information.
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BB) and were highly correlated (r2 = 0.83) (Figure 5). Although the λgc in the entire NARAC case-control dataset is decreased from 1.073 to 1.048 by considering this axis, our analyses indicate that the position of individuals on this axis is almost completely due to this localized inversion. This region is presumably identified by PCA because of the long stretch of linkage disequilibrium caused by the chromosomal inversion.