cannabis five or more times in a month) was used as inclusion criterion for SymCanAD. The rationale for using these definitions was that we wanted to use only those subjects with sufficient exposures to drinking and cannabis use. In the combined sample, 1,801 and 614 subjects met inclusion criteria for SymAlcAD and SymCanAD, respectively. The frequency distributions of SymAlcAD and SymCanAD are shown in Supplementary Figure S2.
