In summary, despite evidence that visual-spatial processing deficits are associated with alcohol and cannabis use, and that oscillatory activity is broadly affected by alcohol and cannabis use, few studies have examined visual oscillatory activity in the context of alcohol and cannabis use disorders. In the current study, we use MEG to study the impact of use disorder on the neural dynamics serving visual-spatial processing by comparing adults who used both cannabis and alcohol and met criteria for AUD and/or CUD, to adults who used both cannabis and alcohol but did not meet criteria for AUD and/or CUD. We specifically focused on cortical oscillatory activity and aimed to decipher the independent effects of alcohol and cannabis use disorders. We hypothesized that altered alpha oscillatory activity would be associated with alcohol use disorder, while aberrant gamma oscillatory activity would be associated with cannabis use disorder.
