However, it is still unclear to what extent rare genetic variation, and the joint effect with common variation, differs between the subtypes of OCD, and how this balance may depend on age of onset and sex. Such findings could encourage a reconsideration of key clinical features of OCD as a means of defining subtypes. Defining clinical subtypes that differ in rare and common variation could accelerate research into biomarkers and novel treatments, eventually helping clinicians offer patients optimal prognosis and treatment.
